Scientists recruited 16 male participants from the Oxford BioBank, a random population-based cohort in the U.K. made up of healthy individuals between the ages of 30 and 50. The participants were broken up into two groups, each given a different dosage of the steroid. After seven days, both groups showed worsening insulin sensitivity, which is the main symptom that can lead to type 2 diabetes.
According to Pofi, “This suggests that we need to more accurately assess GC use in patients to prevent and reduce the undesired effects, especially in patients for which steroid treatment is essential for life.”
More research needs to be done before these findings can be confirmed, and the scientists behind the experiment plan on completing more large-scale studies in the future.
Another important step is to figure out how the steroid treatment could work alongside various diabetes medications and whether or not that would reduce the risk of developing the disease.